Moscow, August 26, Scientists have discovered a unique method that helps treat childhood brain cancer gene level.
Scientists in the United States have identified a new method of combating brain cancer in children. Experts have invented a biological pathway to help fight deadly tumors.
According to the doctors, these pathways destroy the cell process that participates in the process of cancer education.
According to the authors of the survey, this biological pathway destroys the cellular process associated with DIPG (diffusive tumor).
Experts share that any previous attempts to influence the tumor did not give such an effective result. Thus, scientists have discovered a mutation of PPM1D that is very important for cell growth, but experts have not yet managed to attack it.
Now scientists have discovered the vulnerability of THEY, a metabolite that is important for cellular life. Thus, scientists concluded that the PPM1D gene independently determines its own stages of death. According to the doctors, the PPM1D gene that produces THEM is MUP.
When THEY run out of metabolites, the genes switch to NAMPT. Experts have noticed that if you use a drug that suppresses NAMPT, you can achieve the death of cancer cells. “MedicForum,” writes about it.
As previously reported, scientists have disowned the main myths of cancer. Experts said that people create false ideas about how cancer develops, they begin to invent all sorts of diets and exercises, and in fact, only exacerbate the situation. For example, according to experts, people think that the main cause of oncology is frequent stress. Doctors say it’s not like that at all.
Researchers from the United States have discovered a new biological pathway that can be used to improve survival rates among children with an incurable brain cancer called diffuse brain stem cell tumor or DIPG glioma. In the course of the study, its authors suggested that this biological pathway destroys the cellular process associated with DIPG.
Preliminary studies have shown a genetic mutation called PPM1D, which is critical for cell growth and their stress response in the development of glioma. However, earlier attempts to directly attack this PPM1D mutation did not show high efficiency.
And now, researchers have discovered a vulnerability in the metabolic process of creating NAD – a metabolite that is essential for the life of all cells.
Experts call this an amazing and promising new approach to cancer treatment. It turns out that the mutated PPM1D gene independently sets the stages for its own death. The mutated PPM1D has been found to mute another gene called NAPRT, which is key to the production of the NAD metabolite.
When NAD is unavailable, the cells switch to another protein needed to create NAD, called NAMPT. Using a drug that inhibits the production of NAMPT can lead to the death of cancer cells caused by the PPM1D mutation